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Διάλεξη για την Έρευνα και Εφαρμογές στην Ιατρική Μοριακή Γενετική

29.03.2012, Συνεδριακό και Πολιτιστικό Κέντρο Πανεπιστημίου Πατρών

Το Ενδοπανεπιστημιακό Δίκτυο

Έρευνα και Εφαρμογές στην Ιατρική Μοριακή Γενετική

(Άξονες «Γονιδιωματική» & «Βιοπληροφορική»)

(http://mgn.upatras.gr)

διοργανώνει διάλεξη με τίτλο:

"Αποκαλύπτοντας την πολυπλοκότητα του γονιδιώματος του ανθρώπου. Ο συνδυασμός γονιδιωματικής και υπολογιστικής ανάλυσης για τη διάγνωση και θεραπεία αυτοάνοσων νοσημάτων"

“Deciphering the complexity of the human genome. The convergence of genοmics and computational approaches for the diagnosis and treatment of autoimmune diseases”

Ομιλητής

Dr. Dimitris Monos

Director, Immunogenetics Laboratory

Prof. of Pathology & Laboratory Medicine

Perelman School of Medicine, U. of Pennsylvania

Πέμπτη, 29 Μαρτίου 2012, 13.00

Αίθουσα ΙΙ-9, 1ος Όροφος

ΣΥΝΕΔΡΙΑΚΟ & ΠΟΛΙΤΙΣΤΙΚΟ ΚΕΝΤΡΟ ΠΑΝ/ΜΙΟΥ ΠΑΤΡΩΝ

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Dr. D. Monos’ Research Interests Dr. D. Monos’ research interests cover a wide spectrum of Human Leucocyte Antigen (HLA)-related topics. His group, in conjunction with other groups has pioneered the DNA-based methodologies for HLA typing. He has worked on a number of structure/function relationships of HLAs, which are very important for the immune response, and identified associations of HLAs with several diseases, including type 1 diabetes, tuberculoid leprosy, berylliosis, ovarian carcinoma and Crohn’s disease. His work has also contributed on the development of the key concept that the strong linkage disequilibrium observed within the MHC does not simply reflect the significance of several genes within this genomic region for the physiological functioning of the immune system but also for the observed disease associations with the HLAs. Genes within the MHC in coordination or independently of particular HLA alleles generate the disease phenotype. The realization that there are additional genes, besides HLAs within the MHC for predisposing to disease susceptibility has been the guiding principle for the recent intense efforts to fully characterize this genomic region and investigate disease associations with a dense set of SNPs and High-Throughput Sequencing technologies. As the Director of the Immunogenetics Lab at the Children’s Hospital of Philadelphia, he also collaborates with the Stem Cell Transplant team, the Nephrology, Cardiology and Gastroenterology Divisions, and perform research on a number of clinically related projects. His work has been funded by NIH, ADA, JDRF, NMDP and other external sources.

Σημ.: Η διάλεξη θα είναι στα ελληνικά με διαφάνειες στα αγγλικά

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